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Figure 1 2.2 Determination of the instrumental variables Instrumental variables (IVs) are characterized by three pivotal assumptions: (1) Association assumption: There exists a robust correlation between SNPs and exposure factors

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Selective transport of GSH across the ER membrane has been shown in mammalian liver microsomes (Banhegyi et al , 1999), and into the sarcoplasmic reticulum of skeletal muscle (Banhegyi et al , 2003)